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Table 1 Clinical and biochemical index of the patients at baseline

From: A novel MSC-based immune induction strategy for ABO-incompatible liver transplantation: a phase I/II randomized, open-label, controlled trial

  MSC (N = 11) Rituximab (N = 11) P value
Gender (male)(%) 9 (81.8%) 10 (90.9%) 1.000
Age (years) 48.64 ± 7.94 43.64 ± 13.25 0.296
WBC (× 109) 7.32 (3.86–11.60) 9.29 (6.69–15.66) 0.365
PLT (×109/L) 71.00 (47.00–90.00) 104.00 (75.00–201.00) 0.056
AST (U/L) 69.00 (21.00–111.00) 97.00 (53.00–180.00) 0.217
ALT (U/L) 30.00 (9.00–94.00) 99.00 (18.00–233.00) 0.171
ALB (g/L) 32.20 (30.80–35.80) 34.20 (33.20–36.20) 0.773
TBIL (umol/L) 420.73 (38.45–541.73) 590.07 (202.35–702.68) 0.116
ALP (U/L) 99.00 (95.00–124.00) 99.00 (71.00–116.00) 0.478
GGT (U/L) 49.00 (33.00–77.00) 51.00 (42.00–75.00) 1.000
PT (s) 25.60 (20.60–37.60) 33.20 (29.10–38.80) 0.251
INR 2.31 (1.75–3.67) 3.17 (2.71–3.98) 0.270
CREAT (umol/L) 76.00 (45.00–114.00) 71.00 (56.00–174.00) 0.748
BUN (mmol/L) 7.73 (5.01–9.16) 5.35 (3.18–15.44) 0.699
IgM 8.00 (8.00–32.00) 8.00 (8.00–16.00) 0.898
IgG 16.00 (8.00–32.00) 32.00 (2.00–64.00) 0.478
CPS score 11.82 ± 1.66 11.46 ± 1.57 0.604
MELD score 31.00 (30.00–40.00) 40.00 (32.00–40.00) 0.217
Donor age (years) 41.09 ± 15.78 42.73 ± 8.63 0.767
Cold ischemia time(h) 6.00 (6.00–7.50) 6.00 (4.72–7.00) 0.270
Operation time (min) 443.64 ± 41.65 425.64 ± 60.23 0.425
Anhepatic phase time (min) 45.00 (42.00–55.00) 43.00 (40.00–55.00) 0.847
Intraoperative blood loss (mL) 1500.00 (1500.00–2400.00) 1500.00 (1000.00–2000.00) 0.365
Blood transfusion volume
RBC (U) 12.00 (6.00–16.00) 9.50 (7.50–16.00) 0.797
FFP (mL) 2400.00 (2100.00–3600.00) 3050.00 (2000.00–4000.00) 0.606
Cryo (U) 28.00 ± 15.28 36.05 ± 8.08 0.138
  1. Abbreviations: MSC mesenchymal stem cell, WBC white blood cell, PLT platelet, AST aspartate aminotransferase, ALT alanine aminotransferase, ALB albumin, TBIL total bilirubin, ALP alkaline phosphatase, GGT gamma-glutamyl transferase, PT prothrombin time, INR international normalized ratio, CREAT creatinine, BUN blood urea nitrogen, CPS Child-Pugh score, MELD model for end stage liver disease, RBC red blood cell, FFP fresh frozen plasma, Cryo cryoprecipitate