Skip to main content
Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Exosomes derived from human placental mesenchymal stem cells enhanced the recovery of spinal cord injury by activating endogenous neurogenesis

Fig. 7

The therapeutic potential of hpMSC-derived exosomes in SCI recovery and underlying mechanisms (modified from reference [36]). hpMSC-derived exosomes were obtained from hpMSCs through ultracentrifugation. Exosomes stimulated the proliferation of NPCs via activation of MEK/ERK/CREB phosphorylation in vitro which is likely to be mediating their promoting effect on the proliferation of endogenous NPCs and differentiation into matured neurons leading to the functional recovery of SCI observed in vivo

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512