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Table 1 Correlations between EIF5A2 expression and clinicopathologic characteristics of EOC patients

From: EIF5A2 enhances stemness of epithelial ovarian cancer cells via a E2F1/KLF4 axis

Characteristics

All cases

EIF5A2 protein

P value

Low expression

High expression

Age (years, mean)

76

57

55

0.28

Histological type

   

0.201

 Serous

61

25 (41.0%)

36 (59.0%)

 

 Others

15

9 (60.0%)

6 (40.0%)

 

Histological grade

   

0.724

 Well/moderate

10

5 (50.0%)

5 (50.0%)

 

 Poorly

66

29 (43.9%)

37 (56.1%)

 

Lymphatic metastasis

   

0.108

 No

63

30 (47.6%)

33 (52.4%)

 

 Yes

13

4 (30.8%)

9 (69.2%)

 

FIGO stage

   

0.263

 IIIc

58

28 (48.3%)

30 (51.7%)

 

 IV

18

6 (33.3%)

12 (66.7%)

 

Residual disease

   

0.381

 ≤ 10 mm

59

28 (47.5%)

31 (52.5%)

 

 > 10 mm

17

6 (35.3%)

11 (64.7%)

 

Clinical response

   

0.039

 Complete

68

33 (48.5%)

35 (51.5%)

 

 Partial

7

1 (14.3%)

6 (85.7%)

 

 Non-response

1

0 (0.0%)

1 (100.0%)

 

Platinum sensitivity

   

0.014

 Sensitive

60

31 (51.7%)

29 (48.3%)

 

 Resistant*

16

3 (18.8%)

13 (81.2%)

 
  1. *Platinum-resistant was defined as those with relapse within 6 months after primary chemotherapy or progress during the primary chemotherapy