Fig. 3
Characterization of murine hematopoietic cell recovery following sub-lethal irradiation. a Total white blood cells, b red blood cells, c hemoglobin, and d platelet levels overtime are displayed graphically. Irradiation treatment is denoted on the graphs with a dotted red line, and the hBMSC transplant denoted by a dotted blue line. Error bars represent the group standard deviation. e Dot plots of blood cells (CD45+ 7-AAD−) can be seen over time in the irradiated group, revealing the decline at day 3 and recovery by day 10. f Eosinophils, neutrophils, classical monocytes, and macrophages (CD11b+, Gr-1+), and non-classical monocytes (CD11b+, Gr-1low) also show the loss and recovery of the cells over time in the irradiated group. g–i Graphical representation of recovery. Data were analyzed with multiple t tests with Holm-Sidak’s correction and a 0.95% confidence level significance indicated by asterisk * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001. Groups non-irradiated n = 4, irradiated n = 6