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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: MSC-derived small extracellular vesicles overexpressing miR-20a promoted the osteointegration of porous titanium alloy by enhancing osteogenesis via targeting BAMBI

Fig. 3

Characterization of porous titanium alloy. a The surface morphology of macroporous titanium alloy scaffolds were observed by SEM. Scale bar = 500 (100X) and 200 μm (200X). b Compressive tests were conducted using a universal testing machine to examine the biomechanical property of titanium alloy. c The cytocompatibility of Ti and Ti-H were detected using hBM-MSC by CCK-8 test. d The morphology of porous titanium alloy coated by H-sEV-20a via SEM. Scale bar = 400 (100X) and 200 μm (200X). e The release kinetics was measured by CD63 ELISA kit for 14 days for evaluation of the sustained release of sEVs (n = 3, *p < 0.05). f The distribution of sEVs incorporated in HA hydrogel was evaluated by 3D laser confocal microscopy. Scale bar = 200 μm. (*p < 0.05)

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Stem Cell Research & Therapy

ISSN: 1757-6512