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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Andrographolide promotes proliferative and osteogenic potentials of human placenta-derived mesenchymal stem cells through the activation of Wnt/β-catenin signaling

Fig. 6

NanoString analysis of gene-related mRNAs during AP-enhanced osteogenic differentiation of PL-hMSCs. Triplicate samples of total mRNA isolated from PL-hMSCs at day 14 were analyzed using a NanoString Code Set. Left panel shows a heatmap of the 37 candidate genes differentially expressed between growth medium or undifferentiation control (Undiff control), osteo-inductive medium or differentiation control (Diff control), and osteo-inductive medium treated with 2.5 μM AP (Diff+AP). The right panel shows the summary of gene enrichment analysis of the upregulated genes by AP treatment that show statistical significance (P < 0.05) compared to differentiation control

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