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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Heat shock preconditioning mesenchymal stem cells attenuate acute lung injury via reducing NLRP3 inflammasome activation in macrophages

Fig. 4

HS-pretreated UC-MSCs reduce NLRP3 inflammasome activation in lungs and alveolar macrophages. a Protein levels of NLRP3, ASC, pro-Caspase 1, and cleaved-Caspase 1 in murine lung samples were detected by immunoblotting. b The immunoblotting results were quantified by analyzing the gray values. The data are expressed as the mean ± SEM (n = 5 mice/group). c Protein levels of NLRP3, ASC, pro-Caspase 1, cleaved-Caspase 1, and IL-1 β in the macrophage cell line (THP-1 cells) were detected by immunoblotting. b The immunoblotting results were quantified by analyzing the gray values. The data are expressed as the mean ± SEM (n = 3/group). *p < 0.05, **p < 0.01, ***p < 0.001 (all p values were obtained by one-way ANOVA)

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Stem Cell Research & Therapy

ISSN: 1757-6512