Fig. 3

Correlation between miR-424-5p in peripheral blood mononuclear cells (PMBC and inflammatory cytokines a IL7 (r² = 0.442, p = 0.003), b IL8 (r² = 0.385, p = 0.006), c VEGF-C (r² = 0.368, p = 0.008), d CXCR1 mRNA in PBMC (r² = 0.441, p = 0.002) and e PBMC CXCR2 mRNA (r² = 0.564, p < 0.001) and angiogenic markers: f CD45^dimCD34⁺CD133⁺ (r² = 0.43, p = 0.002), g proangiogenic cells (r² = 0.418, p = 0.003), and h fibronectin adhesion assay (r² = 0.396, p = 0.004), across study groups in the plasma. Statistical analysis was carried out using linear regression analysis. IL, interleukin; VEGF, vascular endothelial growth factor; CD, cluster of differentiation. White dots indicated healthy control while black dots indicated T1DM