Table 3 List of significant (p < 0.1) variables selected by multivariable analysis as predictive for osteoblastic and adipocytic differentiation outcome of cultured human bone marrow stromal cells (hBMSCs)
Variable | N of samples | Standardized regression coefficient (95% CI) | p value |
|---|---|---|---|
List of donor- and cell-related variables predictive for osteoblastic differentiation (R2 = 0.552) | |||
Sex | 47 | 20.83 (9.60; 32.05) | 0.001 |
Osteoporosis | 47 | −27.38 (−45.65; −9.1 | 0.004 |
Vitamin D supplementation | 47 | 27.08 (9.58; 44.58) | 0.003 |
CD146+ cells (%) | 47 | 0.28 (0.10; 0.46) | 0.004 |
ALP+ cells (%) | 47 | 0.51 (0.16; 0.87) | 0.005 |
CD14+ cells (%) | 47 | −0.69 (−1.49; 0.11) | 0.089 |
List of donor- and cell-related variables predictive for adipocytic differentiation (R2 = 0.557) | |||
Sex | 47 | −7.95 (−16.24; 0.33) | 0.060 |
Osteoporosis | 47 | 17.36 (8.95; 25.76) | 0.000 |
Alcohol consumption | 47 | −6.85 (−14.96; 1.26) | 0.095 |
CD146+ cells (%) | 47 | −0.21 (−0.36; −0.05) | 0.009 |
ALP+ cells (%) | 47 | 0.31 (0.05; 0.57) | 0.020 |
PDGFRα+ cells (%) | 47 | 0.22 (0.04; 0.39) | 0.016 |
CD362+ cells (%) | 47 | −0.17 (−0.36; 0.02) | 0.073 |