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Table 3 List of significant (p < 0.1) variables selected by multivariable analysis as predictive for osteoblastic and adipocytic differentiation outcome of cultured human bone marrow stromal cells (hBMSCs)

From: Identification of a clinical signature predictive of differentiation fate of human bone marrow stromal cells

Variable N of samples Standardized regression coefficient (95% CI) p value
List of donor- and cell-related variables predictive for osteoblastic differentiation (R2 = 0.552)
Sex 47 20.83 (9.60; 32.05) 0.001
Osteoporosis 47 −27.38 (−45.65; −9.1 0.004
Vitamin D supplementation 47 27.08 (9.58; 44.58) 0.003
CD146+ cells (%) 47 0.28 (0.10; 0.46) 0.004
ALP+ cells (%) 47 0.51 (0.16; 0.87) 0.005
CD14+ cells (%) 47 −0.69 (−1.49; 0.11) 0.089
List of donor- and cell-related variables predictive for adipocytic differentiation (R2 = 0.557)
Sex 47 −7.95 (−16.24; 0.33) 0.060
Osteoporosis 47 17.36 (8.95; 25.76) 0.000
Alcohol consumption 47 −6.85 (−14.96; 1.26) 0.095
CD146+ cells (%) 47 −0.21 (−0.36; −0.05) 0.009
ALP+ cells (%) 47 0.31 (0.05; 0.57) 0.020
PDGFRα+ cells (%) 47 0.22 (0.04; 0.39) 0.016
CD362+ cells (%) 47 −0.17 (−0.36; 0.02) 0.073