Skip to main content
Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: hERG-deficient human embryonic stem cell-derived cardiomyocytes for modelling QT prolongation

Fig. 3

KCNH2 deletion led to the loss of hERG function. a, b Schematic diagrams of FPD and APD by MEA processing. c, d The signals of FPD on different concentrations of E-4031 recorded in WT and KOs. e, f Quantification of FPD. n = 3 independent experiments, unpaired t test. g, h Signals of FPD on different concentrations of dofetilide recorded in WT and KOs. i, j Quantification of FPD. n = 3 independent experiments, unpaired t test. P < 0.05 was considered statistically significant (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001)

Back to article page