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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Clinical-grade human dental pulp stem cells suppressed the activation of osteoarthritic macrophages and attenuated cartilaginous damage in a rabbit osteoarthritis model

Fig. 5

hDPSCs suppress osteoarthritic macrophage activation in a rabbit posttraumatic knee OA model. hDPSC infusion significantly reduced CD11b+CD68+ macrophages in the host articular osteochondral tissues in an OA animal model at a hDPSC dose-dependent manner (a, b). ***P < 0.001. Bars in a upper row and a lower row represent 5mm and 200μm, respectively. hDPSCs, human dental pulp stem cells; OA, osteoarthritis

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Stem Cell Research & Therapy

ISSN: 1757-6512