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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: MRI detection of the malignant transformation of stem cells through reporter gene expression driven by a tumor-specific promoter

Fig. 2

Cell morphology and surface antigens before and after malignant transformation. Compared with MSCs, cells that underwent malignant induction (MTMSCs) became small and demonstrated a spindle-like shape (a). Flow cytometric analysis showed that the expression of the MSC-specific cell surface antigen CD90 was significantly decreased (P<0.01), but that of CD45 was moderately increased after malignant transformation (b)

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Stem Cell Research & Therapy

ISSN: 1757-6512