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Table 2 List of the genes up- or downregulated (> 2 fold) in the iMSC-CdM + MFN1 siRNA group with respect to iMSC-CdM group

From: Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis

Position Symbol RefSeq number Description Fold regulation
A01 ATP5A1 NM_004046 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle − 2.33
A03 ATP5C1 NM_005174 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 − 2.21
A04 ATP5F1 NM_001688 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 − 2.29
A05 ATP5G1 NM_005175 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) − 2.44
A08 ATP5H NM_006356 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d − 2.03
A11 ATP5J2 NM_004889 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 − 2.71
A12 ATP5L NM_006476 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G − 3.01
B02 COX4I1 NM_001861 Cytochrome c oxidase subunit IV isoform 1 − 2.22
B04 COX5B NM_001862 Cytochrome c oxidase subunit Vb − 2.03
B06 COX6A2 NM_005205 Cytochrome c oxidase subunit VIa polypeptide 2 2.32
B08 COX6C NM_004374 Cytochrome c oxidase subunit Vic − 2.3
C02 NDUFA1 NM_004541 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5 kDa − 2.09
C03 NDUFA10 NM_004544 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42 kDa − 2.09
C04 NDUFA11 NM_175614 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7 kDa − 2.14
C06 NDUFA3 NM_004542 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9 kDa − 2.89
C09 NDUFA6 NM_002490 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14 kDa − 3.77
C10 NDUFA8 NM_014222 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19 kDa − 2.57
C11 NDUFAB1 NM_005003 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8 kDa − 3.36
C12 NDUFB10 NM_004548 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22 kDa − 2.52
D05 NDUFB6 NM_182739 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17 kDa − 2.46
D06 NDUFB7 NM_004146 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18 kDa − 2.66
D07 NDUFB8 NM_005004 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19 kDa − 2.5
D08 NDUFB9 NM_005005 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22 kDa − 2.02
D09 NDUFC1 NM_002494 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6 kDa − 2.48
D10 NDUFC2 NM_004549 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5 kDa − 24.21
D12 NDUFS2 NM_004550 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49 kDa (NADH-coenzyme Q reductase) − 2.02
E02 NDUFS4 NM_002495 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18 kDa (NADH-coenzyme Q reductase) − 3.19
E04 NDUFS6 NM_004553 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13 kDa (NADH-coenzyme Q reductase) − 2.73
E06 NDUFS8 NM_002496 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23 kDa (NADH-coenzyme Q reductase) − 2.36
E07 NDUFV1 NM_007103 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51 kDa − 2.46
F01 SDHC NM_003001 Succinate dehydrogenase complex, subunit C, integral membrane protein, 15 kDa − 4.59
F03 UQCR11 NM_006830 Ubiquinol-cytochrome c reductase, complex III subunit XI − 4.87
F08 UQCRQ NM_014402 Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5 kDa − 2.77
F09 ARRDC3 NM_020801 Arrestin domain containing 3 − 3.08
F10 ASB1 NM_001040445 Ankyrin repeat and SOCS box containing 1 − 6.03
F11 CYB561D1 NM_182580 Cytochrome b-561 domain containing 1 − 11.48
F12 DNAJB NM_006145 DnaJ (Hsp40) homolog, subfamily B, member 1 2.15
G01 EDN1 NM_001955 Endothelin 1 2.14
G04 HSPA1B NM_005346 Heat shock 70 kDa protein 1B 2.34
G06 MitoH1 r4_NC_012920 Polycistronic_H1_3 − 2.95
  1. Changes in gene expression between groups were evaluated using RT2 Profiler 96-well PCR array plates. Data analysis was done by the 2CT method on the manufacturer’s web portal (https://geneglobe.qiagen.com/cn/analyze), (QIAGEN, CA, USA)