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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Brain organoid: a 3D technology for investigating cellular composition and interactions in human neurological development and disease models in vitro

Fig. 4

Brain organoids in disease modelling. Non-central nervous system-derived entities including microglia, blood vessels, and viruses can be added to brain organoids to model infected disease and vascular disease, which could help to study their interactions with cells in organoids. Brain organoids derived from patients or that are genetically engineered by CRISPR-Cas9 system to carry genetic variants associated with disease can be used to investigate disease pathogenesis in the nervous system

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Stem Cell Research & Therapy

ISSN: 1757-6512