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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Senescence of donor cells impairs fat graft regeneration by suppressing adipogenesis and increasing expression of senescence-associated secretory phenotype factors

Fig. 4

Immunohistochemistry of perilipin-positive adipocytes. Fat graft samples from the a O-O, b Y-Y, c O-Y, and d Y-O groups at weeks 4 and 12 were stained for perilipin. Fat tissue in the O-O and O-Y groups appeared to be less integrated and displayed immature adipocyte with a smaller size than fat tissue in the Y-Y and Y-O groups at week 12. e Percentage of perilipin-positive areas indicated that all four groups presented fat regeneration over time because perilipin-positive areas in graft samples increased from week 4 to 12. ##p < 0.01 and #p < 0.05 vs. data from the same group at week 4. **p < 0.01 and *p < 0.05 versus data from different groups. Data are presented as the mean ± SD (n = 6 per group)

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