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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Exosomes from miRNA-378-modified adipose-derived stem cells prevent glucocorticoid-induced osteonecrosis of the femoral head by enhancing angiogenesis and osteogenesis via targeting miR-378 negatively regulated suppressor of fused (Sufu)

Fig. 6

The osteogenesis-promoting effects of miR-378-ASCs-Exos in the rat model of GC-induced ONFH. a Reconstructed coronal and transverse images of bones. b Quantitative analyses of trabecular thickness (Tb.Th), trabecular separation (Tb.Sp), bone volume per tissue volume (BV/TV), and trabecular number (Tb.N) in the different treatment groups. c H&E staining of femoral heads in rats receiving different treatments. d Immunohistochemical staining for RUNX2 in samples from the different treatment groups. *P < 0.05, **P < 0.01 compared with the model group. #P < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512