Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Adipose-derived mesenchymal stromal cell-derived exosomes promote tendon healing by activating both SMAD1/5/9 and SMAD2/3

Fig. 5

ADSC-Exos improved the healing of tendon injury. a, h The H&E staining of tendon injury at week 2 and week 4. b–f, i–m The expression of TNMD, collagen I, SCXA, ALP, and Runx2 were detected by immunohistochemistry assay at week 2 (n = 6) and week 4 (n = 6). g, n Quantitative analysis of tenogenic and osteogenic related factors at week 2 (n = 6) and week 4 (n = 6). o Fiber alignment score in each group at week 2 (n = 6) and week 4 (n = 6). p–s Results of biomechanical tests (failure load, stiffness, Young’s modulus) at 4 weeks (n = 3). Bars (H&E), 100 μm; bars (immunohistochemistry), 50 μm. Data are represented as mean ± SD. *vs control group; #vs GelMA group; n = 6. *P < 0.05, **P < 0.01, ****P < 0.0001, #P < 0.05, ####P < 0.0001

Back to article page