Fig. 7
From: Intra-iliac bone marrow injection as a novel alternative to intra-tibial inoculation in rat model
Control tibia (a) and iliac crest (b) of rats. Tibia showing discontinuity of bone, fractures of the subchondral bone, and little hemorrhage at the site of injection (c). Iliac crest with little bone disruption and minute fractures in the bone trabeculae at the site of injection at 1st week post-injection (d) (× 100). Tibia still showing fractures in the subchondral bone, degeneration, and necrosis of chondrocytes of the articular cartilage and discontinuation of the periosteum (e) and iliac crest showing granulation tissue formation at the site of injection at the 2nd week post-injection (f) (× 100). Tibia had fibrous connective tissue formation with thin bone plate formation at the site of injection (g). Iliac crest showed complete re-construction of bone without sign of injection (h) (× 100) (HE stain)