Fig. 6

In vivo evaluation of survival and angiogenesis of transplanted hEMSCs after MI. a Representative micrographs of heart sections showing surviving transplanted cells in hBMSC and hEMSC groups at 28 days after cell injection. Transplanted cells stained with red fluorescent protein (RFP), nuclei stained with 4′, 6-diamidino-2-phenylindole (DAPI). b Quantification of the number of the survived transplanted cells in the infarcted region. c, d Representative micrographs of heart sections, from border and infarct zones, showing arteriole densities (stained with α-smooth muscle actin, green) being significantly higher in hEMSCs, compared to hBMSC and PBS control, in the border zone. e, f Representative micrographs of heart sections, from border and infarct zones, showing capillary densities (stained with isolectin, green) being significantly higher in hEMSCs, compared to hBMSCs and PBS control, in the border zone. Data are expressed as mean ± SEM. n = 5 or 6/group for all the experimental groups