Fig. 4
From: Adipose-derived stem cells therapy effectively attenuates PM2.5-induced lung injury
ADSC transplantation attenuated PM2.5-induced pyroptosis. A Gene set enrichment analysis plot showing the DEGs in the control group vs PM2.5 group enriched in the pyroptosis pathway. B Heat map showing the expression of the genes involved in the pyroptosis process. C The mRNA levels of pyroptotic genes were confirmed by qPCR. D Lysates of lung tissue were subjected to western blotting to determine the expression levels of NOD-like receptor protein 3 (NLRP3), IL-1β, cleaved caspase-1, and gasdermin E (GSDME). β-Tubulin was used as a loading control. In C, N = 5; in D, N = 3; the data are presented as the mean ± SD; asterisk indicates p < .05; double asterisks indicate p < 0.01