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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Cell heterogeneity, rather than the cell storage solution, affects the behavior of mesenchymal stem cells in vitro and in vivo

Fig. 4

Effects of size-based morphological differences on the behavior of UC-MSCs. A Ultrastructure analysis of UC-MSCs of the larger and smaller populations. In addition, the nucleus to cytoplasm ratio was calculated and compared. Nc, nucleus. Scale bar = 5 μm. B Comparison of the number of senescent cells (red arrow) in the populations of UC-MSCs of different sizes. In addition, the positive results were quantified and compared. Scale bar = 100 μm. C Observation of UC-MSCs labeled with GFP. Scale bar = 100 μm. D Immunofluorescence analysis of the heart, liver, and lung from mice after infusion of UC-MSCs of different sizes. Scale bar = 100 μm. All data are presented as the mean ± SD. **p < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512