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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Sox9-expressing cells promote regeneration after radiation-induced lung injury via the PI3K/AKT pathway

Fig. 6

Stem cell markers were involved in RILI. A Nitric oxide synthase 3, endothelial (eNOs) level in mouse serum. Serums were collected after 3, 7 and 14 days after radiation treatment. n = 3. B Nitric oxide (NO) level in mouse serum. Serums were collected after 3, 7 and 14 days after radiation treatment. n = 3. CF Representative IHC staining images of cMyc, Klf4, Oct3/4 and Sox2 after radiation damage in SOX9CreER; RosaDTA mice and control mice (left). The IHC staining scores of cMyc, Klf4, Oct3/4 and Sox2 were assessed (right). *p < 0.05, **p < 0.01, ***p < 0.001 and ***p < 0.0001 as determined by unpaired Student’s t test. n = 3. Scale bar, 50 μm

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