Skip to main content
Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Exosomes derived from adipose-derived stem cells overexpressing glyoxalase-1 protect endothelial cells and enhance angiogenesis in type 2 diabetic mice with limb ischemia

Fig. 4

Wound-healing, transwell, and tube formation assay of the HUVECs. The wound-healing assay found a significantly higher wound closure percentage in the G-ADSC-Exo-treated HUVECs than the ADSC-Exo group and PBS group at 24 h under high-glucose conditions (A, B). The transwell assay showed a significantly larger number of migrated HUVECs in the G-ADSC-Exo group than the ADSC-Exo group and control group (C, D). The tube formation assay showed a significantly higher cumulative tubular length of the HUVECs cocultured with the G-ADSC-Exos than the ADSC-Exo and PBS groups (E, F). All experiments above were repeated three times (n = 3). The one-way analysis of variance was performed to compare data between groups. Scale bar = 100 μm; *P < 0.05; **P < 0.01. G-ADSC-Exos, G-ADSC-derived exosomes

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512