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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Extracellular vesicles derived from mesenchymal stromal cells mediate endogenous cell growth and migration via the CXCL5 and CXCL6/CXCR2 axes and repair menisci

Fig. 2

Effect of MSC-EVs on meniscus regeneration. A Histological and immunohistochemical (IHC) staining of regenerated menisci with or without MSC EV treatment. Samples were stained with HE, safranin-O/fast green, type II collagen (Col II), and type I collagen (Col I) (n = 6; 3 weeks). B Semiquantitative evaluation of meniscus regeneration by modified Pauli’s score. C Quantitative evaluation of the safranin-O-positive area by ImageJ. Three sections per knee were evaluated. Data are the means ± SD. *P < 0.05 according to the Mann-Whitney U test

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