Table 3 Rates of fistula closure and recurrence in patients in the anti-TNF and stem cell groups
Anti-TNF (n=39) | Stem cell (n=30) | P by log-rank test | Unadjusted HR (95% CI) | p-value | Adjusted HR (95% CI) | p-value | |
|---|---|---|---|---|---|---|---|
Cumulative fistula closure, n (%) | 9 (23.1%) | 25 (83.3%) | <0.001 | 8.17 (3.72-17.94) | <0.001 | 3.15 (1.22-8.13) | 0.018 |
1 year | 4 (10.3%) | 18 (60.0%) | |||||
2 year | 6 (15.4%) | 23 (76.7%) | |||||
3 year | 9 (23.1%) | 24 (80.0%) | |||||
Closure time, mean±SD (months) | 36.7±19.2 | 13.7±15.5 | <.001 | ||||
Cumulative fistula recurrence, n (%) | 0 (0%) | 3 (10.0%) | 0.288 | 2.64 (0.9-81.18) | 0.578 | ||
1 year | - | 1 (33.3%) | |||||
2 year | - | 1 (33.3%) | |||||
3 year | - | 1 (33.3%) | |||||
Recurrence time, mean±SD (months) | - | 21.33±13.05 | - | ||||
Follow up, mean±SD (months) | 42.9±16.0 | 39.2±18.6 | 0.385 |