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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Mesenchymal stem cell-derived extracellular vesicles as probable triggers of radiation-induced heart disease

Fig. 4

Effects of hp-MSC-derived EVs on the apoptosis of HUVEC and H9c2 cells. A Representative dot plots of flow cytometry analysis of the apoptosis of HUVEC cells. Quantitative data (n=3) on annexin-V-positive apoptotic HUVEC cells (B) and propidium iodide-labeled necrotic HUVEC cells (C). D Representative dot plots of flow cytometry analysis of the apoptosis of H9c2 cells. Quantitative data (n=3) on the apoptosis (E) and necrosis (F) of H9c2 cells. Non-irradiated-EVs: EVs isolated from conditioned medium of non-irradiated hp-MSCs, irradiated-EVs: EVs isolated from conditioned medium of irradiated hp-MSCs. Values are the mean ± SD. *P < 0.5, **P < 0.1, ***P < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512