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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model

Fig. 4

Effects of LPS-pre EVs on protein expression levels in chondrocytes. a, b Protein expression of aggrecan, COL2A1, and ADAMTS5 in chondrocytes of each group analyzed by western blot (n = 3, one-way ANOVA). c, d Protein expression of aggrecan, COL2A1, and ADAMTS5 in chondrocytes of each group analyzed by immunofluorescence staining (n = 3, one-way ANOVA). e, f Protein expression of aggrecan, COL2A1, and ADAMTS5 in chondrocytes treated with different concentrations of LPS-pre EVs and analyzed by western blot (n = 3, one-way ANOVA). b, d, f Values are presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, one-way ANOVA

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Stem Cell Research & Therapy

ISSN: 1757-6512