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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model

Fig. 5

Effect of LPS-pre EVs on cartilage protection and protein expression in vivo. a Animal experiment model diagram. b Safranin-O and Fast Green and immunofluorescence staining of each group of mouse knee section (n = 6, one-way ANOVA). c OARSI scores in each group (n = 6, one-way ANOVA). d Protein immunofluorescence intensity of aggrecan, COL2A1, and ADAMTS5 in each group (n = 6, one-way ANOVA). c, d Values are presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, one-way ANOVA

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Stem Cell Research & Therapy

ISSN: 1757-6512