Fig. 6

ADSCs inhibit apoptosis in irradiated skin tissue. Representative images of TUNEL-stained cells (A). Nuclei of TUNEL-positive cells are stained green (original magnification, 200×). Percentages of apoptotic cells were significantly decreased in the ADSC group at both 4 and 12 weeks post-irradiation compared with those in the control group. Average OD for analysis of expression of apoptosis-related proteins, BAX and BCL2 (B) (n=6/group). Representative images of skin tissues immunohistochemically stained for BAX and BCL-2 (C). Black arrows indicate positive expression of BAX and BCL-2. The results are expressed as the mean ± SEM. *p < 0.05, **p < 0.01 vs. the control group