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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor-β receptor inhibition

Fig. 6

UCB-MSC-exo-derived specific miRNAs target TGF-β receptors to inhibit myofibroblast differentiation. A List of predicted binding sites for UCB-MSC-exo-miRNAs and their targets. BD Expression levels of TGFBR2 and α-SMA in HDFs treated with miR-21-5p-mimics. EG Expression levels of TGF-βR1 and α-SMA in HDFs treated with miR-125b-5p-mimics; scale bar = 100 μm; *p < 0.05; **p < 0.01; ***p < 0.001; means ± SD; n = 3

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