Table 2 Human gastric cancer-related genes

BUB1

Budding is not inhibited by benzimidazoles

S/T kinase, Mitosis, Spindle checkpoint

[10]

BUB1B

Budding is not inhibited by benzimidazole homolog beta

kinase in spindle checkpoint, cell cycle, mitosis

[10]

NCAPH

Non-SMC condensin 1 complex subunit H

Condensin complex, Mitotic chromosome

[10]

KIF14

Kinesin family member 14

Kinesin superfamily, Microtubule motor proteins

[10]

KIF15

Kinesin family member 15

Kinesin superfamily, Microtubule motor protein

[10]

KIF18B

Kinesin family member 18B

Kinesin superfamily, Microtubule motor protein

[10]

KIF4A

Kinesin family member 4A

Kinesin superfamily, Microtubule motor proteins

[10]

RACGAP1

Rac GTPase activating protein 1

Component of centralspindlin complex, Cytokinesis, Cell growth & differentiation

[10]

RAD-54L

DNA repair and recombination protein RAD54-like

DEAD-like helicase superfamily, Repair of DNA double strand breaks

[10]

TPX2

TPX Microtubule nucleation factor

Cell cycle, Mitotic control of PLK1, G₂/M Transition

[10]

CENPF

Centrosome protein F

Associated with centrosome, Kinetochore complex, Chromosome segregation

[10]

TTK

Dual specificity protein kinase

Mitotic check point, Accurate segregation of chromosome

[10]

SGO

Shugoshin

Protection centromeric cohesion from cleavage during mitotic prophase

[10]

PLK4

Polo family of S/T protein kinase 4

Control centriole duplication

[10]

XRCC2

X-ray repair cross complementing 2

A member of Rec A/Rad51 related protein family, Chromosome stability and repair DNA damage, DNA double strand break

[10]

ClorfI2

Egl-9 family hypoxia inducible factor 1

4-hydroxyprolin in HIFα protein, Cellular oxygen sensor

[10]

FN1

Fibronectin

Cell adhesion, Motility, Opsonization, Would healing, Cell shape

[11]

SERPINE1

Serpin family member 1

Serine protease inhibitor superfamily, Inhibitor of tPA and urokinase inhibitor of fibrinolysis

[11]

SPARC

Secreted protein acidic acid cysteine rich

Cysteine-rich acidic matrix-associated protein

[11]

MLLs

Myeloid/Lymphoid or Mixed-lineage Leukemia protein member

Methyltransferase of histone 3K4

[12]

ARD1A

AT-rich interactive domain-containing protein 1A

SWI/SNF family, Helicase/ATPase. Chromatin remodeling

[12]

EZH2

Enhancer of zeste homolog 2

Histone-lysine-N-methyltransferase enzyme, Chromatin remodeling

[12]

PCAF

p300/CBP-associated factor

Lysine acetyltransferase 2B (KAT2B), Transcriptional coactivator associated with p53

[12]

UTX (KDM6A)

Lysine -specific demethylase 6A

Demethylation of Lysine residue of histone, specifically H3K27

[12]