Fig. 5
From: A systematic summary of survival and death signalling during the life of hair follicle stem cells
The BMP signalling pathway in HFSCs. The BMP pathway is initiated by a BMP dimer connecting with a specific receptor. Then, the dimer phosphorylates and activates R-Smad (Smads 1/5/8), which subsequently associate with the co-Smad partner Smad 4. The T-shaped lines indicate inhibitory interactions involved in this pathway, and the solid arrows indicate activating interactions