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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Melatonin contributes to the hypertrophic differentiation of mesenchymal stem cell-derived chondrocytes via activation of the Wnt/β-catenin signaling pathway

Fig. 4

Melatonin membrane receptor inhibitor blocks melatonin-mediated hypertrophy. a Immunofluorescence staining of melatonin membrane receptors MT1 and MT2 in C3H10T1/2 cells. b–e The mRNA expressions of PTHrP-R (b), RUNX2 (c), COL10A1 (d), and IHH (e) in C3H10T1/2-derived chondrocytes treated as indicated. Gene expressions were normalized to GAPDH mRNA. *P < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512