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Table 1 Summary of sub-retinal injection of cGMP-iPSC-derived photoreceptor precursors in both naïve and disease NHP models

From: cGMP-grade human iPSC-derived retinal photoreceptor precursor cells rescue cone photoreceptor damage in non-human primates

Period of Cocl2 damage

No. of cells

GFP labelled

Period of rescue

Eyes

Naïve

 N.A

40,000–60,000

Non-GFP labelled

3 months

n = 3

Disease/rescue

 1 month

100,000–300,000

GFP labelled

1 month

n = 1

 1 month

100,000–300,000

GFP labelled

3 months

n = 1

 4 months

100,000–300,000

GFP labelled

3 months

n = 2