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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Human Wharton's jelly-derived mesenchymal stem cells alleviate concanavalin A-induced fulminant hepatitis by repressing NF-κB signaling and glycolysis

Fig. 3

RNA sequencing of liver tissues showing alleviation of Con A-induced mouse liver injury by hWJ-MSCs. A Venn diagrams showing significantly enriched gene pathways of Control (Ctrl, also here after in similar experiments) versus Con A group and Con A versus Con A + MSCs group by GSEA analysis. B Bar plot showing normalized enrichment score (NES) of significantly changed GSEA pathways of Control versus Con A group and Con A versus Con A + MSCs group in GSEA analysis. C GSEA analysis showing bile acid metabolism (upper) and fatty acid metabolism (lower), were enriched in indicated groups. D Violin plots showing relative mRNA level of genes involved in bile acid metabolism (left) and fatty acid metabolism (right) in indicated groups, 4 individuals were shown for each group. E and F GSEA analysis showing enrichment of indicated gene sets (upper) and violin plots showing relative mRNA level of involved genes in indicated groups (lower). NES, normalized enrichment score; FDR, false discovery rate; GSEA, gene set enrichment analysis

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Stem Cell Research & Therapy

ISSN: 1757-6512