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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Neural stem cells derived from primitive mesenchymal stem cells reversed disease symptoms and promoted neurogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis

Fig. 3

Transplanted cells homed to the blood, spleen, lungs, and CNS. To determine labeled cells in various organs, collected tissue samples prepared as described in Methods and Materials were subjected to flow cytometry. Symbols, **, #, %, &, §, and ¥, indicate significant difference at p ≤ 0.01 between all experimental conditions: healthy control, healthy control + MSCs, healthy control + NSCs, EAE, EAE + MSCs, and EAE + NSCs. A significant number of labeled cells was found in the blood and spleen, but not lungs of both healthy and EAE mice. Labeled cells were found in the CNS (both brain and spinal cord) of transplanted EAE animals

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Stem Cell Research & Therapy

ISSN: 1757-6512