Fig. 8From: Neural stem cells derived from primitive mesenchymal stem cells reversed disease symptoms and promoted neurogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosisTransplanted cells expressed neural and oligodendrocyte proteins that co-localized with HNA in vivo. a, b Immunohistochemical staining of paraffin sections of the brain and spinal cord with antibodies against cell-specific proteins, TUJ1 (NSCs), OLIG1 (oligodendrocyte progenitor cells), and O4 (ODCs), and counterstained with antibody against HNA. The inserts (on the right) were magnified and overexposed to enhance contrast. Scale bars represent 50 µm scale bars (magnification: 40 ×). c, d Percentage of TUJ1+/HNA+, OLIG2+/HNA+, and O4+/HNA+ cells in the brain and spinal cord sections shown in a and b, respectively (**p ≤ 0.01). TUJ1 staining intensity was greater in both the brain and spinal cord in the case of MSCs, and OLIG2 and O4 staining intensities were greater in the case of NSCsBack to article page