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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: The effect of genetically modified platelet-derived growth factor-BB over-expressing mesenchymal stromal cells during core decompression for steroid-associated osteonecrosis of the femoral head in rabbits

Fig. 7

Assessment of osteoclastogenesis. TRAP staining was performed to evaluate osteoclast presence within the femoral head. a Representative images of each treatment group are shown. b Within the subchondral bone, no differences were noted between treatment groups. Within the bone surrounding the bone tunnel area, the PGK-PDGF-BB-MSC group demonstrated a significantly greater osteoclast density than the other treatment groups (P < 0.05 for all). Scale bar: 100 µm. TRAP tartrate-resistant acid phosphatase, CD core decompression, HG hydrogel, MSC mesenchymal stromal cell, PGK-PDGF-BB-MSC genetically modified phosphoglycerate kinase promoter platelet-derived growth factor-BB over-expressing MSC. *P < 0.05, **P < 0.01, ***P < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512