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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

Fig. 7

Summary of the study. Serum-free conditions promote cell proliferation potential of MSCs in vitro and intrapulmonary engraftment of intravenous delivered MSCs in vivo. SF-MSCs correct cytokine disruptions (e.g., IL-6 production in serum or BALF) caused by BLM administration. Furthermore, SF-MSCs lead to efficiently inhibition of BLM-induced lung inflammation and fibrosis by promoting induction of Tregs into the lung compared with S-MSCs

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Stem Cell Research & Therapy

ISSN: 1757-6512