Skip to main content
Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: A novel minimally invasive OFM technique with orthotopic transplantation of hUC-MSCs and in vivo monitoring of liver metabolic microenvironment in liver fibrosis treatment

Fig. 6

Metabolomic analysis of liver interstitial fluid via OFM sampling combining mass spectrometry detection. A PCA analysis of liver interstitial fluid in normal group (N), model group (M) and hUC-MSCs OFM-treated group (H) based on metabolomic analysis. B Heat maps of normalized metabolite concentrations in liver dialysates. Columns represent the samples, and rows represent the metabolites. The data were already normalized by using mean-centered. C A volcano plot based on the metabolomic data in model group vs. normal group. D A volcano plot based on the metabolomic data in hUC-MSCs OFM-treated group vs. model group. Metabolites with a p value < 0.05 and a fold change (FC) > 2.0 or < 0.5 are highlighted in the volcano plot. E Metabolic pathway analysis between normal group and model group. F Metabolic pathway analysis between hUC-MSCs OFM-treated group and model group

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512