Fig. 1
From: Stem cell-based therapy for ameliorating intrauterine adhesion and endometrium injury
Stem cell-based approaches to uterus regeneration include (1) intravenous stem cells or EV/ Exo, (2) intrauterine injection stem cells or EV/Exo and (3) fabrication of synthetic graft by encapsulating stem cell or EV/Exo therapeutics with biomaterials. After transplantation, stem cells can stimulate the angiogenesis, epithelization and gland regeneration while inhibitory inflammation and endometrial fibrosis, and eventually restore normal uterine structure and function