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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Synergistic stimulation of osteoblast differentiation of rat mesenchymal stem cells by leptin and 25(OH)D3 is mediated by inhibition of chaperone-mediated autophagy

Fig. 1

Leptin enhanced the expression of megalin of rBMMSCs. a Relative mRNA expression of rBMMSCs megalin in growth medium at 8 h; b IF showed leptin enhanced the protein expression of rBMMSCs megalin; c relative quantitative analysis of megalin IF staining; d 25(OH)D3 had no effect on the relative mRNA expression of megalin with or without leptin in osteoblast differentiation medium (ODM) after 8 h; e IF showed 25(OH)D3 did not affect the protein expression of megalin; f relative quantitative analysis of megalin IF staining. (Scale bars = 100 μm. *P < 0.05, **P < 0.01, ***P < 0.001 in comparison with the control group.)

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Stem Cell Research & Therapy

ISSN: 1757-6512