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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: PPARβ/δ accelerates bone regeneration in diabetic mellitus by enhancing AMPK/mTOR pathway-mediated autophagy

Fig. 2

PPARβ/δ agonist accelerates bone regeneration of calvarial defects in diabetic rats. A Schematic illustration of experimental design. B Representative images of μCT regeneration of carvarial defects at 4 and 8 weeks (scale bar = 3 mm). C Quantitative μCT analyses of bone mineral density (BMD, mg/cc) and bone volume/total volume (BV/TV, %) within the original defect position boundary (n = 8). Data are expressed as mean ± SD. The p values were calculated by two-way ANOVA with Tukey’s post hoc test. (NS, not statistically significant, *p < 0.05, ***p < 0.001, ****p < 0.0001)

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Stem Cell Research & Therapy

ISSN: 1757-6512