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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: PPARβ/δ accelerates bone regeneration in diabetic mellitus by enhancing AMPK/mTOR pathway-mediated autophagy

Fig. 6

Autophagy promotes osteogenic differentiation of rBMSCs in high-glucose environment. A ALP staining and ALP activity quantitative analyses of N0, H0, H5 and H5 + 3-MA groups cultured for 7 days of osteogenic induction. B ARS staining and quantitative analyses of rBMSCs after 21 days of osteogenic induction. C qRT-PCR for the osteogenesis-related genes Runx2, Bglap, Col1a1 and Osx after 7 days of osteogenic induction. Data are expressed as mean ± SD. The p values were calculated by one-way ANOVA with Tukey’s post hoc test (*p < 0.05, ****p < 0.0001)

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Stem Cell Research & Therapy

ISSN: 1757-6512