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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Sevoflurane preconditioning promotes mesenchymal stem cells to relieve myocardial ischemia/reperfusion injury via TRPC6-induced angiogenesis

Fig. 2

Sevoflurane preconditioning up-regulated TRPC6, HIF-1α, VEGF and CXCR4 in MSCs under H/R. Protein expressions of TRPC6, HIF-1α, VEGF and CXCR4 in MSCs under H/R (a). mRNA expression of TRPC6 in MSCs under H/R (b). VEGF level detected by ELISA assay in the supernatant of MSCs under H/R (c). Data are shown as Mean ± SEM, n = 3 per group (a), n = 5 per group (b and c). *P < 0.05, **P < 0.01 versus M + O2; #P < 0.05 versus M-O2

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