Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Nonwoven-based gelatin/polycaprolactone membrane loaded with ERK inhibitor U0126 for treatment of tendon defects

Fig. 2

U0126 promoted ectopic tendon formation in nude mice. The cell sheets formed by TSPCs with U0126-treatment or not were implanted into the nude mice. After 6 weeks of transplantation, the samples were collected, and sectioned. A HE staining of the sections, and visualized under polarized microscopy. Scale bar = 200 μm. B Immunohistochemistry (IHC) staining of sections. Anti-Tnmd and Col1a1 antibodies were used for IHC staining to observe their expression in the newly formed tendon-like tissue. The relative intensity was analyzed by Image J software (IHC Toolbox). The data was expressed as mean ± SD (n = 3), *p < 0.05. Scale bar = 100 μm

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512