Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI)

Miyata, Shoko; Saku, Noriaki; Akiyama, Saeko; Javaregowda, Palaksha Kanive; Ite, Kenta; Takashima, Nagisa; Toyoda, Masashi; Yura, Kei; Kimura, Tohru; Nishina, Hiroshi; Nakazawa, Atsuko; Kasahara, Mureo; Nonaka, Hidenori; Kiyono, Tohru; Umezawa, Akihiro

doi:10.1186/s13287-021-02680-4

Stem Cell Research & Therapy

Table 1 A list of immortalized cells from DILI patients

From: Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI)

Cell Name	Gene-1	Gene-2	Gene-3	Gene-4	Parental Cell
iHep2-D9-81	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1	CSII-CMV-hTERT		iPSC-I
iHep2-D9-85	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-cyclin D1	CSII-TRE-Tight-hCDK4R24C	CSII-CMV-hTERT	iPSC-I
iHep3-D9-89	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1	CSII-CMV-hTERT		iPSC-O
iHep3-E1-29	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-cyclin D1	CSII-TRE-Tight-hCDK4R24C	CSII-CMV-hTERT	iPSC-O
iHep2-E2-64	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1	CSII-CMV-hTERT		iPSC-I
iHep2-E2-66	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-hCDK4R24C	CSII-TRE-Tight-cyclin D1	CSII-CMV-hTERT	iPSC-I
iHep3-E2-68	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1	CSII-CMV-hTERT		iPSC-O
iHep3-E2-70	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-hCDK4R24C	CSII-TRE-Tight-cyclin D1	CSII-CMV-hTERT	iPSC-O
iHep2-E3-32	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1	CSII-CMV-hTERT		iPSC-I
iHep2-E3-34	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-cyclin D1	CSII-TRE-Tight-hCDK4R24C	CSII-CMV-hTERT	iPSC-I
iHep2-E3-36	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1	CSII-CMV-hTERT		iPSC-I
iHep3-E3-38	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1	CSII-CMV-hTERT		iPSC-O
iHep3-E3-40	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-cyclin D1	CSII-TRE-Tight-hCDK4R24C	CSII-CMV-hTERT	iPSC-O
iHep3-E3-42	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1	CSII-CMV-hTERT		iPSC-O
iHep2-E3-62	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-hCDK4R24C	CSII-TRE-Tight-cyclin D1	CSII-CMV-hTERT	iPSC-I
iHep3-E3-64	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-hCDK4R24C	CSII-TRE-Tight-cyclin D1	CSII-CMV-hTERT	iPSC-O
iHep4-E4-72	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1	CSII-CMV-hTERT		iPSC-K
iHep4-E4-74	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-cyclin D1	CSII-TRE-Tight-hCDK4R24C	CSII-CMV-hTERT	iPSC-K
iHep4-E4-80	CSII-CMV-hTERT	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1		iPSC-K
iHep4-E4-82	CSII-CMV-hTERT	CSII-CMV-hCDK4R24C	CSII-CMV-cyclin D1		iPSC-K
iHep4-E4-84	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-cyclin D1	CSII-TRE-Tight-hCDK4R24C	CSII-CMV-hTERT	iPSC-K
iHep4-E5-50	CSII-CMV-TetOff-ADV	CSII-TRE-Tight-cyclin D1	CSII-TRE-Tight-hCDK4R24C	CSII-CMV-hTERT	iPSC-K
iHep2-E8-45	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-hCDK4R24C	CSII-TRE-Tight-cyclin D1	CSII-CMV-hTERT	iPSC-I
iHep2-E8-46	CSII-ALB-tetOff-ADV	CSII-TRE-Tight-hCDK4R24C	CSII-TRE-Tight-cyclin D1	CSII-CMV-hTERT	iPSC-I
iHep4-E8-49	CSII-CMV-TetOff-ADV	CSII-TRE-Tight-cyclin D1	CSII-TRE-Tight-hCDK4R24C	CSII-CMV-hTERT	iPSC-K
iHep4-E8-50	CSII-CMV-TetOff-ADV	CSII-TRE-Tight-cyclin D1	CSII-TRE-Tight-hCDK4R24C	CSII-CMV-hTERT	iPSC-K

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