Fig. 4

Receptor expression of COVID-19 ARDS associated cytokines on the cell products. A Flow cytometry analysis demonstrated all cell types express surface receptors for cytokines implicated in the COVID-19 ARDS pathology (except for IL-6); table showing the mean percentage cells that expressed cytokine receptors. Receptors for IL-1β or IL-8 were found to be expressed at a higher percentage in all cell types, while receptor for IL-2 was found to be minimally expressed. All data were analyzed by One-way ANOVA followed by post hoc testing using Tukey’s Multiple Comparisons test with *p ≤ 0.05 as indicated. B Flow cytometry co-expression analysis on three relatively highly expressed cytokine receptors showed that higher proportion of BM-MSCs and HDCs express COVID-19 ARDS cytokine receptors as compared to UC-MSCs. All data are presented as individual and mean values ± SEM, n = 3 biological replicates; each circle represents one data point from one unique biological replicate