Fig. 9
The number of the neutrophils (A), lymphocyte (B), and volume density of inflammatory tissue (C), vessels (D), and bile ducts (E). Prednisolone and MSCs accelerated the replacement of the neutrophil to the lymphocyte population as early as 2 weeks. Prednisolone and cell alleviated inflammation and immune cell migration. Angiogenesis was significantly higher in the cell/prednisolone-loaded group than the control (P = 0.0086), drug-loaded (P = 0.0004), and cell-loaded (P < 0.0001) groups at the 4th week after transplantation. A non-significant acceleration in the bile duct migration and formation was observed in both cell-loaded scaffolds compared to the control and prednisolone-loaded groups