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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: LINC01119 negatively regulates osteogenic differentiation of mesenchymal stem cells via the Wnt pathway by targeting FZD4

Fig. 4

LINC01119 negatively regulated the osteogenic differentiation of MSC. AC qRT-PCR analysis of RUNX2, OSX, OCN mRNA expression in BMSCs transfected with sh-LINC01119 or pLV-LINC01119 after 7 days of osteogenic media treatment. D ALP activity in BMSCs transfected with sh-LINC01119 or pLV-LINC01119 after 7 days of osteogenic media treatment. E Oil red-O staining for BMSCs transfected with sh-LINC01119 or pLV-LINC01119 after adipogenic induction media for 14 days; the arrow indicates the fat formation in brown areas

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